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If a protein does not have any sorting sequence, it stays in the cytosol. Keyword: Protein Sorting Pathways, Subcellular Localization, Protein-Protein Interac. Path determined by a carrier-protein binding to targeting signals. Concepts of Protein Sorting or Targeting Signals and. Received for publication, June 25, 2004, and in revised. In the absence of retention or sorting signals, soluble pro- teins of the secretory.

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